The clastogenic effects of Aflatoxin B 1 ( AFB
نویسنده
چکیده
In this study the effects of AFB1, a mold metabolite, on third instar larval salivary gland polytene chromosomes of Drosophila melanogaster were investigated. The various chromosomal abnormalities (= aberrations) as fragment loss from teminal, semibreak, asynapsis, regional shrinking, ectopic pairing on arms of polytene chromosome, were observed in polytene chromosome slides from third instar larvae which have developed in the medium containing AFB1. It was found that the difference between control and test groups from the point of view of the chromosomal abnormalities is statistically significant (P < 0.05). The possible mechanism of the all chromosomal abnormalities caused by AFB1 is discussed.
منابع مشابه
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تاریخ انتشار 2006